pcDNA/esRAGE plasmid (20 µg) [HM-311]
Plasmid pcDNA/esRAGE contains the cDNA, deriving from alternative splicing of the primary transcript, that corresponds to the secreted isoform of human RAGE (esRAGE). It expresses esRAGE when transiently transfected in mammalian cells. The soluble secreted esRAGE can be recovered from the culture supernatant.
The expressed esRAGE protein contains no tags.
Pubblications in which this product was used:
See Raucci et al. A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10). FASEB J 2008 Jul 4. [Epub ahead of print]