HMGB2 human, LPS-free (500 µg) [HM-151]
HMGB2 is 80% identical to HMGB1 protein, but is encoded by a different gene. It consists of 195 amino acids and has a calculated molecular mass of approximately 22.3 kDa.
The sequence of this product is identical toHomo sapiens.
It contains only trace amounts of LPS (<0.4 ng/mg protein) and it is tested for the ability to induce fibroblast migration.
It has the sequence:
MGKGDPNKPR GKMSSYAFFV QTCREEHKKK HPDSSVNFAE FSKKCSERWK TMSAKEKSKF EDMAKSDKAR YDREMKNYVP PKGDKKGKKK DPNAPKRPPS AFFLFCSEHR PKIKSEHPGL SIGDTAKKLG EMWSEQSAKD KQPYEQKAAK LKEKYEKDIA AYRAKGKSEA GKKGPGRPTG SKKKNEPEDE EEEEE
Buffer: 50 mM HEPES-Na pH 7.9, 500 mM NaCl, 0.5 mM DTT.
Storage: the protein is shipped lyophilized. Once resuspended can be stored frozen at -20°C. To avoid cysteine oxidation, DTT 0.5mM is added during protein purification.
This product is intended for research only, and cannot be used on humans.
Publications where this product was used:
Ronfani et al (2001) Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2. Development 128:1265-73
Complete Name: High Mobility Group 2
Other Names: Amphoterin-2, High mobility group protein 2,HMG-2, high mobility group protein B2, high-mobility group box 2, Amphoterin, HMG2, HMGB2, SBP-2, recombinant HMGB2