A recent research, published two weekes ago, shows that nuclear HMGB1 is essential for the anti-tumor activity of CD8 T cells, particularly in enhancing interferon gamma (IFN-γ) production, a key cytokine in tumor elimination.
Nuclear HMGB1 and anti-tumor immunity Read More »
Emerging research highlights the relevant role of High-Mobility Group Box 1 (HMGB1) in muscular diseases, offering new insights that could inform future therapeutic strategies for SMA.
Spinal Muscular Atrophy and HMGB1 protein Read More »
A recent study has highlighted the significant role of the disulfide form of HMGB1 in liver pathologies related to excessive alcohol consumption.
The role of HMGB1 disulfide form in alcohol-associated liver diseases Read More »
HMGB1 protein plays significant roles in conditions such as liver ischemia-reperfusion (LI/R) injury and Hepatitis B virus (HBV) infection.
World Hepatitis Day: Focusing on HMGB1 in Liver Health Read More »
Recent studies have provide significant insights into the role of High Mobility Group Box 1 (HMGB1) in Alzheimer’s disease (AD), particularly its involvement in neuroinflammation and cognitive decline.
Alzheimer’s Disease Pathogenesis and HMGB1 protein Read More »
Studies have highlighted the significant role of High-Mobility Group Box 1 (HMGB1) in AD, providing new insights and potential therapeutic applications.
HMGB1 as a target in Alzheimer’s Disease Research Read More »
A study just published on ASCO’s Journal of Clinical Oncology focuses on how lung metastasis remains a significant challenge in treating Triple Negative Breast Cancer (TNBC).
Exosomal HMGB1 in Lung-Tropic Metastasis of Triple Negative Breast Cancer Read More »
Recent progresses in proteomics have unveiled promising pathways for early cancer detection and treatment.
New Frontiers in Proteomics: Early Cancer Detection Read More »
On May 20th, World AUTOimmune & AUTOinflammatory Arthritis Day, highlights the global impact of autoimmune and autoinflammatory arthritis, affecting an estimated 450 million people worldwide.
Autoimmune and autoinflammatory arthritis: HMGB1 as a biomarker and therapeutic target Read More »
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