In literature has been demonstrates that HMGB1 induces cell migration by activating RAGE or CXCR4 receptor through a heterologous complex with CXCL12.
Spinal cord injury: HMGB1 heterologous complex with SDF1 (CXCL12) Read More »
A recent study in the journal Frontiers underscores the association between HMGB1 and autophagy in the progression and complications of diabetes mellitus.
HMGB1 and autophagy relationship in the pathogenesis of diabetes Read More »
HMGB1, proinflammatory mediator belonging to the alarmin family, is making waves in asthma research.
During tissue inflamation, HMGB1 protein is secreted by various immune cells and has a dual way of entering the extracellular space.
Asthma research update: the pivotal role of HMGB1 Read More »
HMGBiotech has joined the conference “Goodbye Flat Biology: Next Generation Cancer Models” promoted by EACR, through a poster presentation by Dr. Andrea Lamarca.
Speech at Berlin EACR Conference: Mesothelioma and HMGB1 BoxA Read More »
A recent research has highlighted a groundbreaking discovery concerning the connection between HMGB1 released by mesothelial cells and the development of asbestos-induced mesothelioma.
Unveiling the Mechanism Behind Asbestos-Induced Mesothelioma Read More »
Liam Colley, HMGBiotech’s researcher, gave a speech about “The role of CXCR4 in Triggering Immunosurveillance in the Malignant Mesothelioma Tumor Environment”.
HMGBiotech at CICON- International Cancer Immunotherapy Conference 2023 Read More »
HMGB1 has been shown to play a key role in Parkinson’s disease pathogenesis. Research and studies targeting High Mobility Group Box 1 (HMGB1) protein in Parkinson’s disease (PD) has recently emerged, with promising results in the inhibition of HMGB1.
HMGB1, a Potential Game-Changer in Parkinson’s Research Read More »
Recent studies showed HMGB1’s role in the fight against cancer. HMGB1 is increasingly associated with tumor stages, prognosis, immune response and drug resistance.
HMGB1 could be a game-changer in cancer research Read More »
Latest researches showed that HMGB1 is involved in causing ischemic stroke by ehnancing inflammation and tissue damage in cerebrovascular diseases.
Stroke Research Highlight: HMGB1’s Role in Ischemic Stroke Read More »
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