Recent studies showed HMGB1’s role in the fight against cancer. HMGB1 is increasingly associated with tumor stages, prognosis, immune response, and drug resistance. High Mobility Group Box 1 (HMGB1) protein has a comprehensive role in different tumors and in regulating responses to oxidative damages and cell death associated with oncogenic processes.
The growing interest in HMGB1 as a potential biomarker for cancer progression is due to its concentration changes at different stages of the disease.
This discovery enables the development of HMGB1-targeted treatments and opens a new door in cancer therapy research.
More studies are on the horizon to uncover the full potential of HMGB1.
Read the full articles about the studies:
https://pubmed.ncbi.nlm.nih.gov/36727602/
https://pubmed.ncbi.nlm.nih.gov/36820147/
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