HMGBiotech has joined CICON 2023 through a poster presentation by Dr. Liam Colley.
CICON is the international reference meeting for scientists, clinicians, regulators, drug developers, and patient advocates.
Liam Colley, HMGBiotech’s researcher, gave a speech about “The role of CXCR4 in Triggering Immunosurveillance in the Malignant Mesothelioma Tumor Environment”. During the speech has been highlighted how CXCR4 acts as a hub for anti-tumor immune signaling on malignant mesothelioma cells. CXCR4 is the receptor of CXCL12 chemokine protein: theese proteins create an axis which plays a relevant role in shaping the tumor microenvironment (TME), mainly against dampening immune responses.
The conclusions of the studies about the role of CXCR4 might be exploited to improve current immunotherapies.
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